Chromatography

Advanced porous media for the highest performance in separation applications.

Superior material expertise combined with experienced engineering support services

Known for its leadership and innovative solutions, Porex brings a wealth of experience to the design and manufacturing of porous plastics, porous composites, functionalized porous media, bio-activated porous media and other high-performance porous materials in the separations industry. 

Our POREX® chromatography products and media are:

  • Manufactured from multiple materials, including polyethylene (PE), polypropylene (PP) and sintered polytetrafluorethylene (POREX® Virtek™ PTFE) and can be used on a wide range of applications, including separation columns and sample extraction techniques.
  • Custom designed in a variety of solutions, including chromatography Solid Phase Extraction (SPE) frits, high-throughput automation filters, affinity filters and supports, dissolution filters and protein precipitation filters and media.
SPE Frits and High Throughput Automation Filters

SPE Frits and High Throughput Automation Filters

High-performing frits for the most challenging chromatography applications

Protein Precipitation Media

Protein Precipitation Media

Remove contaminants from protein samples without plugging or breakthrough

Affinity filters and supports

Affinity Filters and Supports

Protect samples with affinity filters and supports

Dissolution filters

Dissolution Filters

Filter out contaminants during the dissolution testing process

SPE Frits and High Throughput Automation Filters

SPE Frits & High Throughput Automation Filters

High-performing frits for the most challenging chromatography applications

POREX offers a variety of PE, PP and porous PTFE filters — commonly known as frits, for use in commercially available SPE columns, cartridges or multi-well SPE plates to facilitate column concentration to a vacuum manifold, needle or collection vessel. Hydrophilic, oleophobic, blended-resin, and functionalized materials are also available for use in the most challenging chromatography applications.

Porex frits and filters offer:

  • Controlled flow for optimized reaction time (kinetic control).
  • Superior resin support due to narrow pore size distribution.
  • Cleanliness and high purity with very low levels of extractables, leachables, and particle shedding.
  • Custom designs in various disc, spherical, and other geometries to help ensure a tight material seal, optimized assembly operation, and no resin by pass.
  • Fast & easy assembly in mass production - rigid structure facilitates manufacturing processes.

APPLICATIONS:

  • Solid Phase Extraction (SPE) Media Supports (Frits) for Columns and Cartridges
  • 48, 96, 384 and 1536 Well Plates
  • Flash Chromatography Supports
  • Low-Pressure Column Supports

POROUS MATERIALS AVAILABLE:  

  • Polyethylene (PE)
  • Polypropylene (PP)
  • POREX® Virtek™ PTFE

AVAILABLE CONFIGURATIONS:  

  • Sheets
  • Rods
  • Tubes
  • Molded 3-D shapes
  • Die cut shapes

 

Related Resources:

pdf download Brochure: Porex Life Science Solutions

Protein Precipitation Media

Remove contaminants from protein samples without plugging or breakthrough

Protein precipitation is widely used in downstream processing of biological products to concentrate proteins and purify them from various contaminants.  POREX® Precipitation Membranes aid in the removal of contaminating lipids, salts and proteins from samples prior to LC-MS/MS without plugging or breakthrough. Designed to retain acetonitrile, methanol and other organic solvents our protein precipitation media solutions:

  • Retain acetonitrile, methanol and other organic solvents.
  • Provide reproducible and consistent results and are chemically inert, hydrophobic, oleophobic, while containing no leachables
  • Increase efficiency through elimination of time-consuming centrifugation and transfer steps.
  • Are independently tested for solvent leakage, nonspecific binding, flow rates and well blockage by LC-MS/MS.
  • Are a PE based solvent support media solution - designed to retain low surface tension organic solvents for extended periods of time without plugging, leakage or breakthrough.

APPLICATIONS:

  • Protein Purification
  • 96 Well Plates
  • High Speed Automation
  • Bioanalytical Analysis
  • Drug Discovery

POROUS MATERIALS AVAILABLE: 

  • Polyethylene (PE)
  • POREX® Virtek™ PTFE

AVAILABLE CONFIGURATIONS: 

  • Sheets
  • Rolls

 

Related Resources:

pdf download Brochure: Porex Life Science Solutions

Protein Precipitation Media detail
Affinity Filters details

Affinity Filters and Supports

Protect samples with affinity filters and supports

POREX® affinity filters and supports are an innovative range of advanced porous materials that enhance functionality through surface modification or sorbent addition. Designed to capture, clean-up, desalt and purify peptides, proteins and oligonucleotides. POREX affinity filters and supports help optimize flow and retention variables and can be used in pipette tips, multi-well plates, spin down and gravity flow centrifuge columns.  Our Porex materials:

  • Aid in the optimization of flow and the retention variables through surface modification and sorbent addition/blending.
  • Help facilitate high resolution with high flow velocity.
  • Have multiple configuration designs for applications such as pipette tips, 48- and 96- well plates, spin columns and gravity flow columns.
  • Offer versatile options including discs, sheets with Controlled Pore Glass (CPG), reverse phase (C8, C18, other), anionic, cationic, all in a homogenous porous matrix.

APPLICATIONS:

  • Spin Columns
  • 48, 96, 384 and 1536 Well Plates
  • Gravity Flow Centrifuge Columns
  • Pipette Tip Filters

POROUS MATERIALS AVAILABLE:  

  • Polyethylene (PE)
  • Polypropylene (PP)
  • POREX® Virtek™ PTFE

AVAILABLE CONFIGURATIONS:  

  • Sheets
  • Molded and Die Cut Discs
  • 3D Shapes
  • Rolls
  • Functionality: embedded carbon, certified porous glass (CPG), reverse phase (C8, C18, other), anionic, cationic, all in a homogenous porous matrix.

Related Resources:

pdf download Brochure: Porex Life Science Solutions

Dissolution Filters

Filter out contaminants during the dissolution testing process

POREX® Dissolution Filters are used in conjunction with pharmaceutical tablet and capsule products to help filter contaminates during the dissolution testing process. Heavy metal free POREX® Dissolution Filters are available in cannula, circular/disk and filter frit designs in a wide variety of porosities and:

  • Meet U.S. Pharmacopeia Standards for elemental impurities
  • Can be used with molecular diagnostics, clinical IVD, infectious diseases and research applications.
  • Will withstand automated assembly equipment and resist breakage due to strong, durable and lightweight construction.
  • Are designed with chemically-resistant media which will tolerate most acids and bases.
  • Offer instant pore size identification with color-coded resins.

 

Cannula Filters

POREX® Cannula Filters are used on the end of a sampling cannula and feature a large surface area and optimized flow rate for an ideal choice in applications with a high presence of particulates.

Material: Porous UHMWPE

Available Sizes: 1, 4, 5, 10, 20, 35, & 70um sizes

 

Filter Frits

POREX® Filter Frits are circular filters used with low-dimension sample probes in applications where it is important to keep the filtration process outside of the vessel.

Material: Porous PE

Available Sizes: 10 & 45um sizes

 

Filter Tips

POREX® Filter Tips are used with low quantities of particulates and flow at the filter bottom.

Material: Porous PE

Available Sizes: 2, 5, 10, 20 & 45um sizes

POREX Filter Tips are available in and can be used on sample cannulas with 1/6” diameter.

 

Related Resources:

pdf download Brochure: Porex Life Science Solutions

Dissolution filters details