Life Sciences – Laboratory Filtration

Chromatography Frits, Media Support, and Filters

Advanced Solutions for Chromatography Frits for More Accurate Results

Supercharge your separation device with a single, powerful frit

In addition to decades of experience engineering customizable chromatography frits for global customers, POREX® porous polymer materials can create a single frit powerful enough to replace the two support frits and the loose beads in the stationary phase. By modifying one frit with your choice of surface treatments and functionalized resins, separation device manufacturers can increase their operational efficiency and get more accurate results. When you collaborate with Porex, the only limitation is your imagination

Affinity Filters and Supports

Porex affinity filters and supports are an innovative range of advanced porous materials that enhance functionality through surface modification or sorbent addition. Designed to capture, clean up, desalt, and purify peptides, proteins, and oligonucleotides. POREX affinity filters and supports help optimize flow and retention variables and can be used in pipette tips, multi-well plates, spin down, and gravity flow centrifuge columns.

Dissolution Filters

Porex Dissolution Filters are used in conjunction with pharmaceutical tablet and capsule products to help filter contaminates during the dissolution testing process. Heavy metal-free POREX Dissolution Filters are available in cannula, circular/disk, and filter frit designs in a wide variety of porosities.

SPE Frits & High Throughput Automation Filters

Porex offers a variety of PE, PP, and porous PTFE chromatography filters — commonly known as chromatography frits, for use in commercially available SPE columns, cartridges, or multi-well SPE plates to facilitate column concentration to a vacuum manifold, needle, or collection vessel. Hydrophilic, oleophobic, blended-resin, and functionalized materials are also available for use in the most challenging chromatography applications.

Protein Precipitation Media

Protein precipitation is widely used in downstream processing of biological products to concentrate proteins and purify them from various contaminants.  Porex Precipitation Membranes aid in the removal of contaminating lipids, salts, and proteins from samples prior to LC-MS/MS without plugging or breakthrough. Designed to retain acetonitrile, methanol, and other organic solvents, our protein precipitation media solutions.

Three chromatography frits sitting on a table
An illustration of a porex chromatography frit

Options for chromatography media support and filters

Key Features & Benefits

Porex chromatography frits and media can be:

    • Manufactured from multiple materials, including polyethylene (PE), polypropylene (PP), and sintered polytetrafluorethylene (POREX Virtek® PTFE) for a wide range of applications, including separation columns and sample extraction techniques.
    • Customized for a variety of solutions, including chromatography Solid Phase Extraction (SPE) frits, high-throughput automation filters, affinity filters and supports, dissolution filters, and protein precipitation filters and media.

Porex chromatography frits and filters offer:

    • Increase operational efficiency
    • Controlled flow for optimized reaction time (kinetic control).

    • Superior resin support due to narrow pore size distribution.

    • Cleanliness and high purity with very low levels of extractables, leachables and particle shedding.

    • Custom designs in various disc, spherical, and other geometries to help ensure a tight material seal, optimized assembly operation and no resin bypass.

    • Fast & easy assembly in mass production – rigid structure facilitates manufacturing processes.

    • Compliance with (EC) 1907/2006 REACH / Regulation (EU) 2019/1021 POP

Lab Technique Configuration Materials Shapes Resins Surface Enhancements
Solid Phase Extraction Column & cartridge frits
Well plate frits
Polyethylene
Polypropylene
Molded 3D Shapes
Rods
Die Cut
Ion Exchange
Reverse Phase
Normal Phase
CPG
Hydrophilicity
Hydrophobicity
Oleophobicity
Custom Options Available
Protein Precipitation Column & cartridge frits
Well plate frits
Desalting column frits
Gravity flow frits
Automation platform frits
Polyethylene
PTFE
Rolls
Sheets
Die cut
Ion Exchange
Reverse Phase
Normal Phase
CPG
Carbon
Hydrophilicity
Hydrophobicity
Oleophobicity
Custom Options Available
Affinity Chromatography Column & cartridge frits
Gravity flow frits
Pipette tip filters
Spin columns
Polyethylene
Polypropylene
PTFE
Sheets
Rods
Tubes
Molded 3D shapes
Die Cut
Ion Exchange
Reverse Phase
Normal Phase
CPG
Carbon
Hydrophilicity
Hydrophobicity
Oleophobicity
Custom Options Available
Flash Chromatography Column & cartridge frits Polyethylene
Polypropylene
PTFE
Sheets
Die cut
Molded 3D shapes
Ion Exchange
Reverse Phase
Normal Phase
CPG
Carbon
Hydrophilicity
Hydrophobicity
Oleophobicity
Custom Options Available
Product Number Airflow
l/hr/cm²
(Min. @70mbar)
Airflow
l/hr/cm²
(Typ. @70mbar)
WEP*
mbar
(Min)
WEP*
mbar
(Typ)
Thickness
(mm)
Max
Temp
°C
Dry Filtration
Efficiency
>99.99%**
BM10 14 30 200 360 1.0 260
BM15 25 84 30 120 1.0 260
BM20 50 90 10 80 1.0 260
BM25 11 20 200 400 1.5 260
BM30 16 50 120 200 1.5 260
BM35 25 60 40 140 1.5 260
BM40 25 55 20 100 1.5 260
BM45 8 18 220 430 2.0 260
BM50 16 40 80 200 2.0 260
BM55 18 50 50 180 2.0 260
BM60 25 50 20 140 2.0 260
BM65 6 12 250 450 3.0 260
BM70 14 32 90 230 3.0 260
BM75 14 35 70 245 3.0 260
BM80 15 40 20 200 3.0 260
BM105 1 2.5 800 1000 1.0 260 0.1µ
BM110 0.75 2 800 110 1.5 260 0.1µ
BM115 0.5 2 820 1150 2.0 260 0.1µ
BM120 0.25 1 840 1400 3.0 260 0.1µ
*WEP = Water Entry Pressure
** Test results to be available in the future
Properties are typical and not meant for specifications. Selected options and adhesives may affect properties
Complete testing data and information is available upon request – all exceeded the standard BFE value of 98%
RoHS, WEEE, REACH Compliant (PFOA Free)

Geometric Options

  • Sheets
  • Rods
  • Tubes
  • Molded 3-D shapes
  • Die-cut shapes

Applications

  • Solid Phase Extraction (SPE) Media Supports (Frits) for Columns and Cartridges
  • 48, 96, 384 and 1536 Well Plates
  • Flash Chromatography Supports
  • Low-Pressure Column Supports
  • Protein Purification
  • High Speed Automation
  • Bioanalytical Analysis
  • Drug Discovery
  • Spin Columns
  • Gravity Flow Centrifuge Columns

Porous Laboratory Components

Watch our On-Demand Webinar

Using Porous Polymers for Filtration

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