Life Sciences – Diagnostics
Sample Preparation Media
Providing sample purification with high analyte concentration
Sample Purification with High Analyte Concentration
Once collected, samples must go through critical preparation steps to enable reliable diagnostic testing. In order to achieve the highest sensitivity, diagnostic tests require purified analytes – free from inhibitors – at a high concentration.
Porous materials offer controlled pore sizes, providing the necessary filtration to normalize sample viscosity and to remove inhibitors. The customizable porous matrix prevents clogging, ensuring a controlled flow, which becomes increasingly important within cartridge-based testing. In addition to removing inhibition, Porex solutions utilize pure materials with low non-specific binding to prevent inhibition from materials and maximize available analyte for optimal test sensitivity
Optional integrated chemistry can simplify workflows by eliminating additional steps to help treat and normalize samples, such as incorporating cell lysis into the filtration step. The structure of Porex materials allows a singular component to achieve multiple steps, reducing assembly cost and simplifying the user protocol. A component can be used as a filter, as well as room temperature reagent storage, providing quick rehydration of reagents and a controlled flow for easy mixing. The structure can also support clinical protocols, like nucleic acid amplification, by incorporating extraction chemistry to perform the analyte isolation process. In addition to supporting test chemistry and sample purification, materials play a vital role in supporting the preparation infrastructure. This includes flow control, venting to prevent contamination, and absorption to prevent leakage of excess sample and used buffer reagents. Whether at home, at the clinic, or in the laboratory, Porex solutions simplify protocols and enable high-sensitivity testing.
Register for our On-Demand Webinar
Using Porous Plastics for Wicking
How it works
Porex’s sample preparation solutions are employed in home-testing protocols, point-of-care (POC) cartridges, and laboratory workflows. With the ability to vary the geometry, pore structure, and material, Porex solutions are designed to perform critical steps in each environment. With the ability to integrate reagents and preparation chemistry, one customizable solution can perform multiple functions with clinical precision, greatly reducing cost and enabling accuracy through a simplified, hands-off workflow. Ultimately, the material properties are tailored to ensure access to pure analyte and high sensitivity, with minimal user effort.
Options for customizing sample collection media
ReadyGo Diagnostics Ltd. Announces its Partnership with Porex
See the lastest on how Porex is enabling precise sample volumes
Related Resources
Molecular Diagnostic application case study
This application case study showcases Porex’s expertise in customized solutions for molecular diagnostics manufacturers. Find out how we delivered an assay cartridge component that maintained FDA approval and reduced production costs with a streamlined assembly process.
Porex Clinical Science Solutions
Clinical science products, media and filters from Porex Corporation are design optimized to help ensure performance,
purity, accuracy and reproducibility in demanding IVD,
molecular and clinical diagnostic sample preparation, liquid
handling and microfluidic applications.
Saliva Collection Media Brochure
Explore custom-engineered POREX® saliva collection media designed to expedite and improve the accuracy of saliva test results.
Certified Pure Porex brochure
Certified Pure Porex Materials and Filters were
rigorously tested by third-party analytical, clinical and life cycle microbiology laboratories to help insure performance, accuracy and reproducibility in demanding healthcare and life science applications.
Select Samples
Explore our library of our most common capabilities samples to discover firsthand what is possible with custom materials.
Ask An Engineer
Take a first step by having a quick consultation with one of our application engineers.