Life Sciences – Diagnostics

Sample Collection Media

Making Patient Samples Accessible for Downstream Testing

Sample Collection Media for Precise Volume Collection with High Analyte Recovery

Accurate diagnosis starts with the proper collection of a sample, as the pre-analytic stages of diagnostic testing can lead to erroneous results if not performed correctly. A precise volume uptake followed by a high analyte release combined with the removal of inhibitors ensures the consistency of diagnostics workflows.

Porous materials offer controlled pore sizes and structures, allowing for precise volume uptake as well as inhibitor removal crucial in sample collection. For challenging analytes, customized material solutions can reduce nonspecific binding. Integrating sample collection materials into direct sample-to-test devices eliminates sample loss via transfer steps to prepare a higher concentration of analyte for higher sensitivity.

In addition, sample sufficiency indicators can visually demonstrate when samples are ready to reduce user error in at-home settings. Optional integrated chemistry can simplify workflows by eliminating additional steps to help treat and normalize samples, such as incorporating cell lysis into the collection step or buffering in samples with wide variations of pH.

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This is a pregnancy test that includes urine sample collection media.

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Using Porous Plastics for Wicking

How it works

Porex’s sample collection solutions are employed in custom collection devices for infectious disease, drugs of abuse, and genetic testing enabling superior specimen collection of nasal, saliva, vaginal, sputum, blood, breath, and other sample types. The design of these collection materials ensures consistent sample uptake and optimal analyte recovery, reducing pre-analytic errors.

ReadyGo Diagnostics Ltd. Announces its Partnership with Porex

See the lastest on how Porex is enabling precise sample volumes

Options for customizing sample collection media

Key Features & Benefits

  • Pure materials which enhance sample integrity
  • High recovery of analytes
  • Customized capillary material structures that absorb quickly and consistently
  • Enhanced functionality with custom integrated chemistry
  • Diverse raw material options
  • Sheets
  • Rolls
  • 3D geometric shapes
  • Molded & die-cut discs
  • Blood
  • Urine
  • Saliva
  • Nasal
  • Vaginal
  • Respiratory
  • Bloodborne pathogens
  • STI
  • Tuberculosis
  • Antibiotic Resistance
  • Drugs of Abuse
  • Genetic Testing

FAQ’s

How to choose the right swab for collecting a sample?

When choosing a sample collection swab there are several important factors to consider including sample type, yield and quality. Also, different swab materials will perform better or worse based on the type of testing being performed (e.g., microbiology, molecular diagnostics or clinical diagnostics). For example, cotton swabs can inhibit some organisms in microbiological analysis and flocked nylon swabs will yield a higher quantity of DNA for PCR testing.

Porex HRM (high-release media) swabs are the best option for those searching for a synthetic fiber, such as polyester, with precise sample volume collection. They can also be customized to avoid non-specific binding and ease of use for self-collection situations.

What are the differences between a flocked swab and a Porex HRM swab?

The main difference between flocked swabs and Porex high-release media (HRM) swabs is the base material. Flocked swabs are made of short nylon fibers that are spray coated onto a tip. In contrast, Porex HRM swabs are made of a bi-component fiber material that includes polyethylene and polyester and is formed through a nonwoven bonding process. Unlike flocked swabs, the Porex swab can be customized to capture and release a specific sample volume.

Porex HRM can also include a color-changing sample volume sufficiency indicator, which alerts users when adequate sample has been collected.

What are the best swabs to use for PCR testing?

The best Porex sample collection material for downstream PCR testing is our Porex HRM. Porex HRM is made of synthetic polyester fiber and can be tailored for specific sample volume uptake and release. It can also remove impurities from complex sample types, such as saliva, resulting in a purer sample for molecular diagnostics.

Importantly, cotton materials should be avoided, due to potential inhibition in downstream PCR workflows.

Porous Laboratory Components

Download our Tech Brief:

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Webinar

In this webinar, explore the integration of Porex materials with ReadyGo’s chemistry and design platforms, which have simplified measured laboratory procedures — like pipetting and cell lysis prep — into cost-effective workflows suitable for any user.

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