Inhaler manufacturers have found a valuable solution in porous polymers to enhance device performance and reduce costs. These versatile components play a crucial role in filtration, wicking, and capillary action within inhalers, thereby improving drug delivery efficiency and effectiveness. By incorporating Porex’s porous polymers in their designs, manufacturers can optimize manufacturing costs while elevating device performance.
Filtration, Wicking, & Capillary Action: Enhancing Inhaler Performance with Porous Polymers
Inhalation devices require precise filtration to ensure medication purity and prevent contamination. Customized porous polymers enable enhanced filtration efficiency by controlling pore size, effectively filtering out contaminants, and improving patient safety. Additionally, these components excel in promoting efficient wicking and capillary action, ensuring optimal fluid transfer within inhalers. By leveraging porous polymers, manufacturers can achieve cost savings, enhance material purity, and optimize drug delivery, ultimately benefiting patients by improving the efficacy and reliability of inhalation therapies.
Inhaler Design Challenges & Solutions
Design Challenge 1: Contaminant Removal
Maintaining a high level of purity in inhalation devices is crucial for ensuring the effectiveness of therapies. In the case of portable oxygenators used in at-home care, the design challenge lies in effectively removing contaminants from the air while providing a quieter operation. Custom porous polymers can provide a three-in-one solution by absorbing and diffusing the sound generated by compressed air, resulting in a more silent operation. At the same time, these porous polymers act as efficient inlet filters, removing contaminants and maintaining air purity. By incorporating a multifunctional component, manufacturers can achieve contaminant removal and noise reduction by utilizing the same component while reducing design complexity and cost.
Design Challenge 2: Backflow Inhibition & Precise Delivery
When delivering medication to the central nervous system via nasal spray, backflow contamination, and precise delivery are critical design challenges. Custom components made of clean and biocompatible materials prevent leachables and extractables from contaminating the device and ensure safe delivery to the patient. They also can customize flow rate to inhibit backflow contamination and enable precise and focused delivery to spaces such as the nasal cavity. These components can also be tailored to meet the specific requirements of chemical compatibility, formulation viscosity, and metered dosing rates to ensure reliable and safe delivery.
Design Challenge 3: User Error Reduction & Consistent Deposition
In dry powder inhalers (DPIs) and portable nebulizers, reducing user errors caused by subjective inhalation techniques is a significant challenge for achieving consistent drug deposition. Poor inhaler technique and irregular respiration can lead to backflow and inconsistent delivery. Custom components can overcome these challenges by preventing backflow through unique formulations and customized pore structure, thereby creating independent inspiratory flow rates that mitigate risk within the device. Our components also provide methods for aerosolizing the drug, while acting as a sterile barrier. This feature ensures accurate dosing and consistent deposition in the lungs, while ensuring sterility for the lifetime of the device.
Design Challenge 4: Fine Particle Filtration & Volumetric Efficiency
Soft mist metered dose inhalers (MDIs) present a design challenge in achieving effective fine particle filtration while maintaining high volumetric efficiency. The smaller particle size generated by MDIs requires efficient filtration to prevent aerosol residue in the mouth after inhalation. Custom components made from porous polymers can reach submicron filtration levels, effectively managing particle fractions and ensuring the desired therapeutic effect. Additionally, these components offer high volumetric efficiency, allowing effective use of the reservoir and optimizing medication release.
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Solving Inhalation Design Challenges with Porous Polymers
By addressing these design challenges with custom components made from Porex porous polymers, inhalation device manufacturers can improve performance, ensure purity and sterility, reduce user errors, and achieve cost savings through reduced complexity and increased efficiency. Porex components can also offer solutions for mixed particle sizing with large- and small-molecule combinations, optimizing effective drug delivery regardless of the formulation. These versatile components provide a reliable and efficient solution across various inhaler components, offering comprehensive value in developing inhalation devices.
Enhancing Inhalation Drug Delivery With Porous Polymers
Incorporating Porex porous polymers into inhalation devices presents a significant opportunity for inhaler manufacturers to achieve cost savings while enhancing device performance. These components ensure the highest quality, safety, and efficacy by addressing key design challenges related to contaminant removal, precise dosing, optimal drug deposition, and medication waste reduction. With Porex’s expertise and collaborative approach, manufacturers can unlock the full potential of their inhalation devices, delivering improved patient outcomes and cost-efficient solutions in the evolving field of respiratory therapies. For more information, ask our expert engineers how to solve your design challenges or request a sample.
This article originally appeared on Drug Delivery & Development.